Naloxone

What you need to know

Naloxone, also known as Narcan, is a medication that can reverse the effects of an opioid overdose. Naloxone binds more effectively to the opioid receptors in the brain, temporarily removing the opioid and their harmful effects. This, in turn, reverses the respiratory depression that can lead to a fatal opioid overdose.
Once administered, Naloxone will start to work in approximately 1-5 minutes. Naloxone stays active in the body for 60-90 minutes. Since Naloxone only temporarily removes the opioids from the opioid receptors, opioids will return back to the receptors and overdose symptoms can return. It is important to always call 911 before administering naloxone outside of a medical or hospital setting.
Naloxone is indicated for individuals who:

• • Currently use opioids or have a history of opioid use
  • Are at risk for opioid overdose
  • Do not have previous hypersensitivity to Naloxone Hydrochloride
  • Have contact with individuals who use opioids, and are at risk for opioid overdose